Vita Colon Relief
Prebiotic Probiotic (Sunfiber) (L.Acidophilus and L.Bifidus) in Chewable Flavored Tablets, no water needed.
Why Lactobacillus Acidophilus and Lactobacillus Bifidus?
Produce lactic acid, which creates acidic media in the upper GI tract. This environment is favorable for the beneficial bacteria, but it inhibits the growth of acid sensitive pathogenic bacteria.
Produce a variety of natural antibiotics in the intestine, such as lactocidin, lactobacillin,lactobreven and acidolin.
Produce the enzyme lactase, which aids in the digestion of lactose and milk sugar.
Why Sunfiber
Probiotic are living friendly Bacteria beneficial to the human body, intestinal probiotics that lives in the Gastrointestinal tract “ the digestive system” namely LacticBacteria and Bifidobacteria which should predominate, presenting a barrier to invading organisms. The majority of the intestinal microflora in a healthy person should be good bacteria. The intestinal microflora provides protection against a broad range of pathogens as well as yeasts such as Candida albicans. The greater the imbalance, the greater the symptoms. The use of probiotics may be the most natural, safe and common sense approach for keeping the balance of the intestinal function.
Probiotics Functions
Enhancement of epithelial barrier integrity: Intestinal Probiotic enhance intestinal barrier function, under normal physiological conditions, intestinal barrier is maintained by several factors like mucus production, water and chloride secretion and epithelial cells that form tight junction.
Disruption of epithelial barrier may occur in several clinical conditions such as enteric infections, celiac diseases and infection bowl disease, enhancement of epithelial barrier integrity may be an important mechanism through which the probiotic bacteria benefit in these disease conditions.
The competition for space to adhere between indigenous bacteria and exogenous pathogens result in the competitive exclusion of pathogenic bacteria (Competitive exclusion refers to physical blocking of pathogenic bacteria colonization by probiotic bacteria from their favourite site such as intestinal villus, goblet cells and colonic crypts).
Inhibition of Pathogenic Bacteria
Lactobacilli and B. cereus have been reported to produce various metabolites which have inhibitory effect on pathogenic. Lactobacillus acidophilus has been reported to produce acidophilin, lactocidin and acidolin and L. plantarum produces lactolin (Nicin and diplococcin are among the anti-metabolites produce by the bad bacteria Streptococci.
Interfere with virulence of the harmful Bacteria
From the recent research, it has been concluded that quorum sensing regulates the virulence expression in probiotics which may interfere with the signalling system avoiding the onset of virulence in pathogenic bacteria.
The probiotic bacteria such as Lactobacillus, Bifadobacterium and B. cereus strains degrade the auto-inducers of pathogenic bacteria by enzymatic secretion or production of auto-inducer antagonists which render the quorum sensing bacteria mute and deaf.
Anti-inflammatory effect
Studies show that the anti-inflammatory response of the probiotic bacteria has been achieved through variety of mechanisms mainly through attenuation and inhabitation of the inflammatory affect of the pathogenic bacteria.
References:
J Clin Gastroenterol 2008 Sep;42 Suppl 3 Pt 1:S111-5.Understanding why probiotic therapies can be effective in treating IBD.
Nutr. 2010 Mar;140(3):690S-7S. Epub 2010 Jan 27.
Guidance for substantiating the evidence for beneficial effects of probiotics: probiotics in chronic inflammatory bowel disease and the functional disorder irritable bowel syndrome.
Br. J Ntr 2002 Sep;88 Suppl 1:S51-7.
Probiotics and intestinal health effects: a clinical perspective.
Probiotics: their role in the treatment and prevention of disease.
J Intern Med 2005 Jan;257(1):78-92.
Probiotics and gastrointestinal diseases
Scand J Gastroenterol 2003;(239):15-23.
Probiotics in gastroenterology: indications and future perspectives
Aliment Pharmacol Ther 2007 Dec;26 Suppl 2:133-48.
Review article: Probiotics in gastrointestinal and liver diseases.
Expert Rev Gastroenterol Hepatol 2008 Jun;2(3):337-55.
Rationale for probiotic treatment strategies in inflammatory bowel disease.
Rev Recent Clin Trials 2008 Sep;3(3):167-84.
or therapeutic benefit in inflammatory bowel diseases: review of clinical trials of probiotics, pre-biotics and synbiotics.
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